The American Academy of Neurology (AAN) and the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) offer a new guideline on how to determine what genetic tests may best diagnose a person’s subtype of limb-girdle or distal muscular dystrophy.
A recent article in The New York Times reported on celiac disease, an autoimmune disorder of the gut triggered by the gluten proteins in wheat and other grains, and its connection to the human brain. Upon analysis of several cases, treating an autoimmune disease of the gut (by avoiding gluten) resolved what looked like a debilitating disorder of the brain.
Autoimmune encephalopathy, dementia, and epilepsy are not rare, are potentially treatable, and the diagnosis is aided by testing autoantibody profiles in serum and cerebral spinal fluid. These autoantibodies target neuronal nuclear and cytoplasmic antigens, and have a high predictive value for occult cancer.
- Dementia, Autoimmune Evaluation [A Test in Focus]
- Encephalopathy, Autoimmune Evaluation [A Test in Focus]
- Epilepsy, Autoimmune Evaluation [A Test in Focus]
- Autoimmune Aquaporin-4 Myopathy in Neuromyelitis Optica Spectrum (NMO)
- The Diagnosis of Autoimmune Encephalopathies, Dementias, and Epilepsies [Communiqué]