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Mayo Medical Laboratories Helps Solve Medical Mystery with Special Testing

Mayo Medical Laboratories Helps Solve Medical Mystery with Special TestingGreg Widseth, a 47-year old Polk County attorney, was suddenly hit by a rare disease that prompted his immune system to attack his brain cells, resulting in as many as 60 seizures a day. Special blood and spinal fluid tests developed by Mayo Medical Laboratories confirmed that Widseth had antibodies known to target certain brain cells. Read the full article to learn more about autoimmune disorder testing and treatment.

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The Challenges of Testing For and Diagnosing Porphyrias

The Challenges of Testing For and Diagnosing Porphyrias [Communiqué]The porphyrias are a group of inborn errors of metabolism caused by enzymatic defects in the heme biosynthetic pathway. Depending upon the specific type of porphyria suspected, certain tests are more informative than other assays. Ordering a battery of tests does not enhance the quality of patient care. Rather, a stepwise diagnostic approach is the most effective means of ruling in or out a specific porphyria.

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Short Myelitis Lesions in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorders

Short Myelitis Lesions in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum DisordersShort transverse myelitis is considered non-characteristic of neuromyelitis optica (NMO) spectrum disorders (NMOSDs). Mayo Clinic researchers conducted a study, recently published in Jama Neurology, to determine the frequency of short lesions at the initial myelitis manifestation of NMOSD and to compare the demographic, clinical, and radiological characteristics of aquaporin-4-IgG (AQP4-IgG) seropositive and seronegative STM.

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